As summer comes to an end, many people start to notice changes in their energy levels and overall well-being. Getting out of bed in the morning may feel more difficult, concentration may become harder, and everyday activities can require more effort than usual.

Unexplained fatigue and low mood are often attributed to the end of the holiday season or the approaching autumn. However, they may also be linked to underlying physical conditions that can be detected through laboratory testing. As the days become shorter, changes in daylight exposure can affect the body’s hormonal balance, sleep–wake cycle and the processes involved in mood regulation. This period may also bring to light nutrient deficiencies or hormonal imbalances that have been present for months but only begin to cause noticeable symptoms when the body is under increased strain.

The symptoms of unexplained fatigue can often overlap with those associated with a reduced thyroid function (hypothyroidism) or vitamin D deficiency. Reduced thyroid function slows the body’s metabolism and may lead to tiredness, drowsiness and difficulty concentrating. Similar symptoms may occur in cases of vitamin B12 deficiency, while prolonged stress and associated changes in cortisol levels may also affect energy levels and overall wellbeing. For this reason, it is important to determine whether the symptoms are primarily related to psychological factors or an underlying physical condition.

Laboratory testing can provide valuable information when investigating these symptoms. TSH, fT3, and fT4 tests can help assess thyroid function, while vitamin D (25-OH vitamin D), vitamin B12, and cortisol testing can help identify deficiencies or hormonal changes that may contribute to persistent fatigue and feeling unwell.

If your symptoms have lasted for several weeks or are becoming more pronounced, laboratory testing may help identify the underlying cause and, where appropriate, enable treatment to begin as soon as possible. Contact us to find out which laboratory tests may be appropriate for you.

Frequently Asked Questions

Can a reduced thyroid function cause low mood?
Yes. Reduced thyroid hormone production can be associated with fatigue, low energy, low mood, and difficulty concentrating.

Why is vitamin D testing important at the end of summer?
Although we generally get more sunlight during the summer months, vitamin D levels can still be low depending on an individual’s lifestyle and sun exposure. Low vitamin D levels may contribute to fatigue and reduced well-being.

Which laboratory tests can help identify the possible causes?
Testing TSH, fT3, fT4, vitamin D, vitamin B12 and cortisol can provide valuable information about the possible underlying causes of these symptoms. When should I consider having laboratory tests?
If fatigue and a general feeling of being unwell persist for several weeks or do not improve despite getting enough rest, laboratory testing may help identify the underlying cause.