COVID packages

Price of Siemens Health. SARS-COV-2 IgG package: 5 500 HUF

Package discount: – %
Type of tests 1 pcs
Number of tests 1 pcs

The test is designed for the qualitative and quantitative determination of neutralizing IgG antibodies against SARS-CoV-2.

Description:

The test is designed for the qualitative and quantitative determination of neutralizing IgG antibodies against SARS-CoV-2.

Antibodies produced against the structural proteins of the virus include spike and nucleocapsid antibodies. The spike is a transmembrane glycoprotein consisting of two regions (S1 and S2). S1 controls the recognition and binding to the host cell’s viral receptor (ACE2), is largely made up of the receptor binding domain (RBD) and is highly immunogenic. S2 facilitates viral membrane fusion with the host cell and entry. In most patients, antibodies appear approximately 1-3 weeks after the onset of symptoms and are produced in both symptomatic and asymptomatic infections. Nearly parallel production of IgM and IgG antibodies was observed in symptomatic patients with confirmed SARS-CoV-2 infection. IgM eventually disappears, but IgG remains detectable in the majority of patients. In symptomatic disease, the antibody titre may be higher, although further data are needed to confirm this. Similar to the currently available vaccines, SARS-CoV-2 Total (COV2T) and SARS-CoV-2 IgG (sCOVG) tests target the S1 RBD region of the virus and primary data suggest that antibodies targeting this region may have a neutralizing effect. The identification of specific antibodies associated with neutralization may play an important role in the detection of the immune response against SARS-CoV-2 virus.

Antibody screening is used to test immunization; however, it is in itself not suitable for detecting acute infection!
Seropositivity can be caused by vaccination, previous illness or current infection. To exclude the latter, PCR testing of an upper respiratory tract specimen is required.
In immunosuppressed patients, antibody response is not always detectable.
Antibody levels can decrease below detectable levels over time after the infection has resolved, which does not necessarily mean that immunity has ceased.

Only values expressed in BAU/ml are comparable between laboratories.

Advia Centaur recommended range (Cut off): Non-reactive: < 1.00 index Reactive: ≥ 1.00 index.

Tests:

  • Infection serology: COVID-19 infection: Siemens Healthcare SARS-COV2-IgG SCovG QC

Price of Biomérieux SARS-COV-2 IgM antibody package: 5 500 HUF

Package discount: – %
Type of tests 1 pcs
Number of tests 1 pcs

Időpontfoglalás

The test is designed for the qualitative and quantitative determination of neutralizing IgM antibodies against SARS-CoV-2.

Description:

The test is designed for the qualitative and quantitative determination of neutralizing IgM antibodies against SARS-CoV-2.

Antibodies produced against the structural proteins of the virus include spike and nucleocapsid antibodies. The spike is a transmembrane glycoprotein consisting of two regions (S1 and S2). S1 controls the recognition and binding to the host cell’s viral receptor (ACE2), is largely made up of the receptor binding domain (RBD) and is highly immunogenic. S2 facilitates viral membrane fusion with the host cell and entry. In most patients, antibodies appear approximately 1-3 weeks after the onset of symptoms and are produced in both symptomatic and asymptomatic infections. Nearly parallel production of IgM and IgG antibodies was observed in symptomatic patients with confirmed SARS-CoV-2 infection. IgM eventually disappears, but IgG remains detectable in the majority of patients. In symptomatic disease, the antibody titre may be higher, although further data are needed to confirm this. Similar to the currently available vaccines, SARS-CoV-2 Total (COV2T) and SARS-CoV-2 IgG (sCOVG) tests target the S1 RBD region of the virus and primary data suggest that antibodies targeting this region may have a neutralizing effect. The identification of specific antibodies associated with neutralization may play an important role in the detection of the immune response against SARS-CoV-2 virus.

In immunosuppressed patients, antibody response is not always detectable.
The antibody levels (IgM and IgG) may fall below detectable levels over time after the infection has progressed, which does not necessarily mean that immunity is lost.
IgM levels increase during the first 2-3 weeks of infection, so positivity indicates recent infection.

IgM positivity over 1.0

Tests:

  • Infection serology: COVID-19 infection: Biomérieux SARS-CoV-2 IgM

Price of Laboratory package for SARS-COV-2-specific immune response: 9 000 HUF

Package discount: 18.2%
Type of tests 1 pcs
Number of tests 2 pcs

Időpontfoglalás

SARS-CoV-2 IgG and IgM antibody test from venous blood.

Description:

SARS-CoV-2 IgG and IgM antibody test from venous blood.

Antibodies produced against the structural proteins of the virus include spike and nucleocapsid antibodies. The spike is a transmembrane glycoprotein consisting of two regions (S1 and S2). S1 controls the recognition and binding to the host cell’s viral receptor (ACE2), is largely made up of the receptor binding domain (RBD) and is highly immunogenic. S2 facilitates viral membrane fusion with the host cell and entry. In most patients, antibodies appear approximately 1-3 weeks after the onset of symptoms and are produced in both symptomatic and asymptomatic infections. Nearly parallel production of IgM and IgG antibodies was observed in symptomatic patients with confirmed SARS-CoV-2 infection. IgM eventually disappears, but IgG remains detectable in the majority of patients. In symptomatic disease, the antibody titre may be higher, although further data are needed to confirm this. Similar to the currently available vaccines, SARS-CoV-2 Total (COV2T) and SARS-CoV-2 IgG (sCOVG) tests target the S1 RBD region of the virus and primary data suggest that antibodies targeting this region may have a neutralizing effect. The identification of specific antibodies associated with neutralization may play an important role in the detection of the immune response against SARS-CoV-2 virus.

The detection of the antibody (IgG) is used to test for immunization; however, it is in itself not suitable for the detection of acute infection. It is not possible to assess infectivity without a specific PCR test.In immunosuppressed patients, antibody response is not always detectable.
The antibody levels (IgM and IgG) can decrease below detectable levels over time after the infection has progressed, which does not necessarily mean that immunity is lost.
Only values expressed in BAU/ml are comparable between laboratories.

Advia Centaur recommended range (Cut off): Non-reactive: < 1.00 index Reactive: ≥ 1.00 index.

IgM positivity over 1.0.

When both antibodies are tested together:

  • In the case of negative IgG and IgM, the patient has not yet had an infection or has had an infection for more than 3 months and the antibody levels are already low.
  • Positive IgM, negative IgG – a patient who has been newly infected for less than 2 weeks (this result does not exclude the possibility that the patient has previously been infected or vaccinated but has already had a decrease in antibody levels). In this case this person is most likely to be infectious.
  • Positive IgM and IgG – a patient who has been newly infected or re-infected (even after vaccination) for more than 2 weeks (2-4 weeks). In this case, the test person is most likely to be infectious.
  • Positive IgG and negative IgM – Previously infected or vaccinated patient (more than 4 weeks). To the best of our knowledge, this person is no longer infectious.

Tests:

  • Infection serology: COVID-19 infection: Siemens Healthcare SARS-COV2-IgG SCovG QC, Biomérieux SARS-CoV-2 IgM

Price of Post-COVID laboratory package: 6 400 HUF

Package discount: 7.2%
Type of tests 3 pcs
Number of tests 24 pcs

Időpontfoglalás

Preanalytical information: 12-hour fast before blood collection is required.

After COVID-19 infection, many people have an increased risk for developing a blood clot.
D-dimer, one of the products of fibrin degradation, is produced in the breakdown process following clot formation. The D-dimer measurement is used to determine whether the patient has a factor that has activated the body’s blood clotting mechanism increasingly.

Description:

After COVID-19 infection, many people have an increased risk for developing a blood clot.
D-dimer, one of the products of fibrin degradation, is produced in the breakdown process following clot formation. The D-dimer measurement is used to determine whether the patient has a factor that has activated the body’s blood clotting mechanism increasingly.

Tests:

  • Inflammatory parameters: C-reactive protein (ultra-sensitive, CRP)
  • Blood count with 22 parameters: Blood count: white blood cell (WBC), red blood cell (RBC), hemoglobin (HGB), hematocrit (HCT), mean cell volume (MCV), mean cell (MCH), mean cell hemoglobin concentration (MCHC). Differential count parameters (expressed in % and absolute value): neutrophils (NEUT), lymphocytes (LYMPH), monocytes (MONO), eosinophils (EOS), basophils (BASO), large unstained cells (LUC). Thrombocyte parameters: thrombocyte/platelet (PLT), mean platelet volume (MPV), platelet distribution width (PDW), plateletcrit (PCT).
  • Blood clotting (Coagulation): D-Dimer

Price of Extended Post-COVID laboratory package: 21 385 HUF

Package discount: 4.6%
Type of tests 9 pcs
Number of tests 40 pcs

Időpontfoglalás

Preanalytical information: 12-hour fast before blood collection is required.

Our extended post-COVID laboratory package is used to check health status after COVID-19 infection.

Description:

Our extended post-COVID laboratory package is used to check health status after COVID-19 infection.

COVID-19 infection increases the risk of myocardial damage and blood clotting.
This can even lead to a heart attack. Symptoms may include chest pain or shortness of breath.
COVID-19 infection can also have adverse effects on liver, kidney and muscle function, and increase inflammatory processes as well as it damages thyroid function.

D-dimer, one of the products of fibrin degradation, is produced in the breakdown process following clot formation. The D-dimer measurement is used to determine whether the patient has a factor that has activated the body’s blood clotting mechanism increasingly.

Troponins are proteins involved in muscle contraction of skeletal and cardiac muscle fibres. Troponin types include C, T and I. Cardiac-specific troponin T and/or I are corresponding markers of a possible myocardial damage. After myocardial damage, blood troponin I and T levels are elevated as early as 3-4 hours after myocardial damage and can remain elevated for several weeks, making them a suitable marker of e.g. myocardial infarction.

Tests:

  • Liver function: direct bilirubin, total bilirubin, gamma-glutamyl transferase (GGT), aspartate aminotransferase (AST, GOT), alanine aminotransferase (ALT, GPT)
  • Kidney function: direct bilirubin, total bilirubin, carbamide (Urea, N, BUN), creatinine/ EGFR
  • Inflammatory parameters: alkaline phosphatase (ALP), C-reactive protein (ultra-sensitive, CRP), lactate dehydrogenase (LDH), erythrocyte sedimentation
  • Muscle metabolism: creatine kinase (CK), creatine kinase-MB (CK-MB)
  • Cardiac function: cardiac troponin I (Tn I)
  • Thyroid function: anti-thyroid peroxidase antibody (anti-TPO)
  • Regulation of thyroid hormones: thyroid stimulating hormone (TSH)
  • Function of the hematopoietic system: ferritin, D-Dimer
  • Blood count with 22 parameters: Blood count: white blood cell (WBC), red blood cell (RBC), hemoglobin (HGB), hematocrit (HCT), mean cell volume (MCV), mean cell (MCH), mean cell hemoglobin concentration (MCHC). Differential count parameters (expressed in % and absolute value): neutrophils (NEUT), lymphocytes (LYMPH), monocytes (MONO), eosinophils (EOS), basophils (BASO), large unstained cells (LUC). Thrombocyte parameters: thrombocyte/platelet (PLT), mean platelet volume (MPV), platelet distribution width (PDW), plateletcrit (PCT)

Price of post-COVID PLUS laboratory package: 36 865 HUF

Package discount: 5.1 %
Type of tests 12 pcs
Number of tests 45 pcs

Időpontfoglalás

Preanalytical information: 12-hour fast before blood collection is required.

Our post-COVID PLUS laboratory package is used to check health status after COVID-19 infection.

Description:

Our post-COVID PLUS laboratory package is used to check health status after COVID-19 infection.

COVID-19 infection increases the risk of myocardial damage and blood clotting.
This can even lead to a heart attack. Symptoms may include chest pain or shortness of breath.
COVID-19 infection can also have adverse effects on liver, kidney and muscle function, and increase inflammatory processes as well as it damages thyroid function.

D-dimer, one of the products of fibrin degradation, is produced in the breakdown process following clot formation. The D-dimer measurement is used to determine whether the patient has a factor that has activated the body’s blood clotting mechanism increasingly.

Troponins are proteins involved in muscle contraction of skeletal and cardiac muscle fibres. Troponin types include C, T and I. Cardiac-specific troponin T and/or I are corresponding markers of a possible myocardial damage. After myocardial damage, blood troponin I and T levels are elevated as early as 3-4 hours after myocardial damage and can remain elevated for several weeks, making them a suitable marker of e.g. myocardial infarction.

Under increased tension, the production of active B-type natriuretic peptide (BNP) and inactive N-terminal pro B-type natriuretic peptide (NT-proBNP) is increased in the myocardium. The increased presence of the peptides in the blood means that the heart is able to provide appropriate blood supply by increased work. This change can refer to muscle damage to the heart.

Tests:

  • Carbohydrate metabolism: glucose (GLU, fasting)
  • Liver function: direct bilirubin, total bilirubin, gamma-glutamyl transferase (GGT), aspartate aminotransferase (AST, GOT), alanine aminotransferase (ALT, GPT)
  • Kidney function: direct bilirubin, total bilirubin, carbamide (Urea, N, BUN), creatinine/ EGFR), uric acid
  • Inflammatory parameters: alkaline phosphatase (ALP), C-reactive protein (ultra-sensitive, CRP), lactate dehydrogenase (LDH), erythrocyte sedimentation
  • Muscle metabolism: creatine kinase (CK), creatine kinase-MB (CK-MB
  • Cardiac function: cardiac troponin I (Tn I)
  • Thyroid function: anti-thyroid peroxidase antibody (anti-TPO)
  • Regulation of thyroid hormones: thyroid stimulating hormone (TSH)
  • Blood clotting (Coagulation): D-Dimer, prothombrin+INR (Pt+INR), N-terminal pro B-type natriuretic peptide (NT-proBNP)
  • Function of the hematopoietic system: ferritin, D-Dimer
  • Blood count with 22 parameters: Blood count: white blood cell (WBC), red blood cell (RBC), hemoglobin (HGB), hematocrit (HCT), mean cell volume (MCV), mean cell (MCH), mean cell hemoglobin concentration (MCHC). Differential count parameters (expressed in % and absolute value): neutrophils (NEUT), lymphocytes (LYMPH), monocytes (MONO), eosinophils (EOS), basophils (BASO), large unstained cells (LUC). Thrombocyte parameters: thrombocyte/platelet (PLT), mean platelet volume (MPV), platelet distribution width (PDW), plateletcrit (PCT)
  • Reticulocyte parameters: reticulocyte (% RETIC), reticulocyte (abs RETIC)